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GeezerVison is showing blast.ncbi.nlm.nih.gov — BLAST: Basic Local Alignment Search Tool

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Basic Local Alignment Search Tool

BLAST finds regions of similarity between biological sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance. Learn more
The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.

News

Thu, 4 Jun 2026

Searching the ClusteredNR database just got much faster.


The new indexed ClusteredNR database for Protein BLAST is here!

More BLAST news...

Web BLAST

Nucleotide query->Nucleotide database
Translated Nucleotide query->Protein database Protein query->Translated Nucleotide database
Protein query->Protein database

Enter organism common name, scientific name, or tax id.

  • Human
  • Mouse
  • Rat
  • Microbes

Standalone and API BLAST

  • Download BLAST
    Get BLAST databases and executables
  • Use BLAST API
    Call BLAST from your application
  • Use BLAST in the cloud
    Start an instance at a cloud provider

Specialized searches

  • SmartBLAST
    Find proteins highly similar to your query
  • Primer-BLAST
    Design primers specific to your PCR template
  • Global Align
    Compare two sequences across their entire span (Needleman-Wunsch)
  • CD-search
    Find conserved domains in your sequence
  • IgBLAST
    Search immunoglobulins and T cell receptor sequences
  • VecScreen
    Search sequences for vector contamination
  • CDART
    Find sequences with similar conserved domain architecture
  • Multiple Alignment
    Align sequences using domain and protein constraints
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