Welcome to 6.8701

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  Home Page Poster Home Page Poster       1

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Class Syllabus and Schedule

• Attachment

  MLCB_25_Class_Schedule (Updated Oct 28).pdf MLCB_25_Class_Schedule (Updated Oct 28).pdf       4

        attachment 1441459 0

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• Attachment

  MLCB25_Syllabus.pdf MLCB25_Syllabus.pdf       5

        attachment 1441505 0

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Lecture Slides

• Attachment

  Lecture01_Introduction_FA25.pptx Lecture01_Introduction_FA25.pptx       1

        attachment 1417903 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  Lecture02_ExpressionClusteringClassification_F25.pptx Lecture02_ExpressionClusteringClassification_F25.pptx       2

        attachment 1417905 0

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• Attachment

  Lecture03_SingleCellGenomics_F25.pptx Lecture03_SingleCellGenomics_F25.pptx       3

        attachment 1420175 0

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• Attachment

  Lecture04_DynamicProgramming_HMMs_BLAST_F25.pptx Lecture04_DynamicProgramming_HMMs_BLAST_F25.pptx       4

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• Attachment

  Lecture05_Epigenomics_HMMs_F25.pptx Lecture05_Epigenomics_HMMs_F25.pptx       5

        attachment 1423544 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  Lecture06_RegulatoryGenomics_F25.pptx Lecture06_RegulatoryGenomics_F25.pptx       6

        attachment 1425433 0

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• Attachment

  Lecture07_RegulatoryNetworks_F25.pptx Lecture07_RegulatoryNetworks_F25.pptx       7

        attachment 1427499 0

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• Attachment

  Lecture08_IntroToProteinStructure_F25.pdf Lecture08_IntroToProteinStructure_F25.pdf       8

        attachment 1429053 0

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• Attachment

  Lecture09_10_AlgorithmsForProteinStructure.pdf Lecture09_10_AlgorithmsForProteinStructure.pdf       9

        attachment 1431666 0

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• Attachment

  Lecture11_ProteinLanguageModels_PLMs.pdf Lecture11_ProteinLanguageModels_PLMs.pdf       10

        attachment 1438604 0

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• Attachment

  Lecture12_DNALanguageModels.pdf Lecture12_DNALanguageModels.pdf       11

        attachment 1438606 0

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• Page

  Lecture 13: Drug Development Lecture 13: Drug Development       24

        wiki_page 1342784 0

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• Page

  Lecture 14: Intro. Small Molecules Lecture 14: Intro. Small Molecules       25

        wiki_page 1342785 0

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• Page

  Lecture 15: Generating Small Molecules Lecture 15: Generating Small Molecules       26

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• Page

  Lecture 16: Training Deep Networks Lecture 16: Training Deep Networks       27

        wiki_page 1342787 0

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• Page

  Lecture 17: Disease Association Mapping Lecture 17: Disease Association Mapping       28

        wiki_page 1342788 0

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• Page

  Lecture 18: Quantitative Trait Mapping Lecture 18: Quantitative Trait Mapping       29

        wiki_page 1342789 0

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Lecture Transcriptions

• Attachment

  MLCB24 Lecture Transcription.pdf MLCB24 Lecture Transcription.pdf       1

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Course Notes

• Attachment

  MLCB25_Course_Notes.pdf MLCB25_Course_Notes.pdf       1

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Recitation Materials

• Attachment

  pset_0_walkthrough.pptx pset_0_walkthrough.pptx       4

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• Attachment

  recitation_2_slides.pptx recitation_2_slides.pptx       5

        attachment 1420930 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  pset2-walkthrough.pdf pset2-walkthrough.pdf       6

        attachment 1430238 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  pset3-walkthrough.pdf pset3-walkthrough.pdf       7

        attachment 1439823 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
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  Recitation9pptx.pptx Recitation9pptx.pptx       8

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  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  Final Project Guidelines (Recitation Slides).pdf Final Project Guidelines (Recitation Slides).pdf       9

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  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete

Project Resources

• Attachment

  Final Project Guidelines (Recitation Slides).pptx Final Project Guidelines (Recitation Slides).pptx       1

        attachment 1462586 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  Mid-course Report Instruction 2025.pdf Mid-course Report Instruction 2025.pdf       2

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  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  ProjectProposal_Template.docx ProjectProposal_Template.docx       3

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  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  PreviousPaperDescription_Template.docx PreviousPaperDescription_Template.docx       4

        attachment 1342823 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  MLCB23.suggested_papers_list.xlsx MLCB23.suggested_papers_list.xlsx       5

        attachment 1342824 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  paper_summary_example1.pdf paper_summary_example1.pdf       6

        attachment 1342825 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  paper_summary_example2.pdf paper_summary_example2.pdf       7

        attachment 1342826 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  paper_summary_example3.pdf paper_summary_example3.pdf       8

        attachment 1342827 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  final_report_example_1.pdf final_report_example_1.pdf       9

        attachment 1428693 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  final_report_example_2.pdf final_report_example_2.pdf       10

        attachment 1428694 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  final_report_example_3.pdf final_report_example_3.pdf       11

        attachment 1428695 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  project_proposal_example_1.pdf project_proposal_example_1.pdf       12

        attachment 1428696 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  project_proposal_example_2.pdf project_proposal_example_2.pdf       13

        attachment 1428697 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  project_proposal_example_3.pdf project_proposal_example_3.pdf       14

        attachment 1428698 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete

Problem Set Solutions

• Attachment

  MLCB25_PSET1_Solutions.ipynb MLCB25_PSET1_Solutions.ipynb       1

        attachment 1436492 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete

Quiz Resources

• Attachment

  MLCB_Practice_Quiz_Solutions.pdf MLCB_Practice_Quiz_Solutions.pdf       9

        attachment 1443968 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  MLCB_Practice_Quiz.pdf MLCB_Practice_Quiz.pdf       10

        attachment 1443971 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  recitation-1107-review.pdf recitation-1107-review.pdf       11

        attachment 1445166 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  Recitation_10_Answers.pdf Recitation_10_Answers.pdf       12

        attachment 1445220 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  MLCB_Review_Session_2.pptx MLCB_Review_Session_2.pptx       13

        attachment 1449378 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete
• Attachment

  Recitation_11_Answers.pdf Recitation_11_Answers.pdf       14

        attachment 1449380 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete

Quiz Solutions

• Attachment

  MLCB_Fall_2025_Quiz_Solutions.pdf MLCB_Fall_2025_Quiz_Solutions.pdf       1

        attachment 1451564 0

  Score at least   Must score at least   to complete this module item Scored at least   Module item has been completed by scoring at least   Score at least  % Must score at least  % to complete this module item Scored at least  % Module item has been completed by scoring at least  % View Must view in order to complete this module item Viewed Module item has been viewed and is complete Mark done Must mark this module item done in order to complete Marked done Module item marked as done and is complete Contribute Must contribute to this module item to complete it Contributed Contributed to this module item and is complete Submit Must submit this module item to complete it Submitted Module item submitted and is complete