GV

GeezerVison

The World Wide Web, restored to 800 pixels of glory.

Home|About|Gaming cabinet|Archives|How it works|Starter sites

On this site

  • Main page
  • Contents
  • Current events
  • Random article
  • About Wikipedia
  • Contact us
  • Help
  • Learn to edit
  • Community portal
  • Recent changes
  • Upload file
  • Special pages
  • Search
  • Donate

This view

  • Original page
  • New address

GeezerVison is showing en.wikipedia.org — Enzyme inducer - Wikipedia

This article may be too technical for most readers to understand. Please help improve it to make it understandable to non-experts, without removing the technical details. (July 2025) (Learn how and when to remove this message)

An enzyme inducer is a type of drug that increases the metabolic activity of an enzyme, either by binding to the enzyme and activating it, or by increasing the expression of the gene coding for the enzyme.[1] One of the examples of enzyme inducers can be Cytochrome P450[2] enzymes, which will help to metabolize the drugs faster in the organism.

Enzyme inducers are important in the pharmaceutical field to learn drug interactions.[3] Studies show that certain drugs will increase the activity of the inducer, examples could be antibiotics.[4] It is the opposite of an enzyme repressor. There are specific types of enzyme inducers[5] that create cytoprotective pathways that play a role in prevention and treatment of cancer and other diseases including cardiovascular disease and neurodegenerative diseases.

Enzyme inducers can be either naturally occurring or synthetically made. These inducers can be naturally occurring, like compounds in cruciferous vegetables, or synthetically developed for therapeutic purposes.

See also

  • Enzyme activator
  • Enzyme inhibitor
  • Regulation of gene expression

References

  1. ↑ Stanbury PF, Whitaker A, Hall SJ (2013). Principles of Fermentation Technology (2nd ed.). Elsevier. ISBN 9781483292915. Retrieved 1 August 2016.
  2. ↑ Jing Li; Chengde Zhang; Shiwen Wu, Jiao Xue; Ke Chen; Zixin Deng; Dongqing Zhu (May 5, 2025). "Science Direct". login.proxy.wexler.hunter.cuny.edu. Retrieved 2025-05-03.{{cite web}}: CS1 maint: multiple names: authors list (link)
  3. ↑ Hakkola, Jukka; Hukkanen, Janne; Turpeinen, Miia; Pelkonen, Olavi (May 5, 2025). "Inhibition and induction of CYP enzymes in humans: an update". Archives of Toxicology. 94 (11): 3671–3722. doi:10.1007/s00204-020-02936-7. ISSN 1432-0738. PMC 7603454. PMID 33111191.
  4. ↑ Chandra, D, Kale, RK. "Web of Science". login.proxy.wexler.hunter.cuny.edu. Retrieved 2025-05-03.{{cite web}}: CS1 maint: multiple names: authors list (link)
  5. ↑ Dinkova-Kostova, Albena T (2010). "Exceptionally Potent Inducer of Cytoprotective Enzymes: ELUCIDATION OF THE STRUCTURAL FEATURES THAT DETERMINE INDUCER POTENCY AND REACTIVITY WITH Keap1". The Journal of Biological Chemistry. 285 (44): 33747–33755. doi:10.1074/jbc.M110.163485. PMC 2962473. PMID 20801881.

External links

  • Hepatic enzyme inducers
  • Hepatic enzyme inhibitors


Stub icon

This enzyme-related article is a stub. You can help Wikipedia by adding missing information.

  • v
  • t
  • e
Stub icon

This article about medicinal chemistry is a stub. You can help Wikipedia by adding missing information.

  • v
  • t
  • e
Retrieved from "https://en.wikipedia.org/w/index.php?title=Enzyme_inducer&oldid=1329933593"
Categories:
  • Medicinal chemistry
  • Enzymes
  • Metabolism
  • Enzyme stubs
  • Medicinal chemistry stubs
Hidden categories:
  • Articles with short description
  • Short description matches Wikidata
  • Wikipedia articles that are too technical from July 2025
  • All articles that are too technical
  • Wikipedia articles needing page number citations from August 2016
  • CS1 maint: multiple names: authors list
  • All stub articles
You are visitor 01402503 — GeezerVison does not store the pages you look up.
Best viewed with Netscape Navigator 4.7 or Internet Explorer 6 at 800×600. No cookies required.