If you have issues during installation, then here is troubleshooting wiki:

https://github.com/pythonnet/pythonnet/wiki/Troubleshooting-on-Windows,-Linux,-and-OSX

pip install pythonnet

See https://pypi.python.org/pypi/pythonnet. Wheels on Windows are available.

pip install git+https://github.com/pythonnet/pythonnet

or download the zip archive of master branch (or run git clone https://github.com/pythonnet/pythonnet) and run these commands from unzipped directory:

pip install .

or from pull requests, e.g.:

pip install git+https://github.com/yagweb/pythonnet@add_scope

• https://ci.appveyor.com/project/pythonnet/pythonnet/branch/master

Select job name ⇒ artifacts

The current Nuget packages are severely outdated, for the time being, please build the binaries yourself. We cannot provide support for the Nuget packages right now, in particular not for the ones that are created from forks.

• https://www.nuget.org/packages/pythonnet/2.3.0-py27-dotnet
• https://www.nuget.org/packages/pythonnet/2.3.0-py35-dotnet
• https://www.nuget.org/packages/pythonnet_py27_dotnet/
• https://www.nuget.org/packages/pythonnet_py35_dotnet/
• progress

conda install -c conda-forge pythonnet

• https://anaconda.org/conda-forge/pythonnet