This repository contains analysis code supporting the manuscript:
SatSeq: An in vivo genotype to phenotype map of the metastatic functions of STING
Deyell, M. et al. (manuscript in preparation)
The directories in this repository each contain separate parts of the analysis:
Code for creating a STINGVariant-Barcode map based on PacBio sequencing of variant STING. Then, using this map to assign variants to cells in the 10x scRNA-seq data.
Code and barcode-level data behind FACS and bulk_fitness results
Analysis-specific folders that use these datasets to produce the final manuscript figures.
If you use this code, please cite the associated SatSeq manuscript. Citation information will be updated once the manuscript is available.