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GeezerVison is showing github.com — DNA-Seq

README.md

Welcome to Just-DNA-Seq

Open-source personal genomics — upload your VCF, get longevity insights, disease risks, 5,000+ polygenic risk scores, and epigenetic clocks in minutes. Runs entirely on your machine.

Key Repositories

Repo What it does
just-dna-lite The platform: Reflex web UI, annotation modules, PRS, AI Module Creator
just-prs Pure-Python PRS engine — 5,000+ PGS Catalog scores, validated against PLINK2 (r = 1.0)
just-biomarkers 44 epigenetic clocks from methylation data (Horvath, PhenoAge, DunedinPACE, …)
# Try just-dna-lite in three commands
git clone https://github.com/dna-seq/just-dna-lite.git && cd just-dna-lite
uv sync && uv run start
Other repositories

Pipelines & tools

  • dna-seq – WDL sequencing pipelines
  • prepare-annotations – Ensembl annotation data pipeline
  • neural_networks – Deep learning for genetic phenotype prediction

Legacy (first-generation OakVar modules)

  • oakvar-longevity, longevity2reporter, just_longevitymap, just_drugs, just_cancer, just_cardio, just_coronary, just_lipidmetabolism, just_thrombophilia, superhumanreporter

Connect

just-dna.life · Telegram · arXiv preprint

Supported by ROGEN, HEALES, IBIMA, Systems Biology of Aging Group. Core developers also contribute to Longevity Genie.

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  1. just-dna-lite just-dna-lite Public

    lite and fast version of just-dna-seq personalized genomic platform

    Python 143 14

  2. just-prs just-prs Public

    Tool and library with ui to compute polygenic risk scores

    Python 7 5

  3. just-biomarkers just-biomarkers Public

    methylation and other biomarkers

    Python 2 1

  4. reflex-mui-datagrid reflex-mui-datagrid Public

    reflex wrapper for reflex-mui-datagrid

    Python 4 1

Repositories

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Showing 10 of 45 repositories
  • longevity-loci Public

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    dna-seq/longevity-loci's past year of commit activity
    Python 0 0 1 0 Updated Nov 12, 2026
  • just-dna-compiler Public

    Just-dna-lite annotation module specification

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    dna-seq/just-dna-compiler's past year of commit activity
    Python 0 MIT 0 0 0 Updated Nov 12, 2026
  • just-module-creator Public

    Claude code plugin to author and publish modules

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    dna-seq/just-module-creator's past year of commit activity
    Python 0 MIT 2 0 0 Updated Nov 12, 2026
  • just-dna-registry Public

    An annotation module catalog for just-dna-lite

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    dna-seq/just-dna-registry's past year of commit activity
    Python 1 MIT 0 0 0 Updated Nov 12, 2026
  • mitoage Public

    Next version of mitoage

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    dna-seq/mitoage's past year of commit activity
    TypeScript 0 MIT 0 0 0 Updated Nov 12, 2026
  • just-biomarkers Public

    methylation and other biomarkers

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    dna-seq/just-biomarkers's past year of commit activity
    Python 2 MIT 1 0 0 Updated Nov 10, 2026
  • manuscript-skills Public

    Prepare AI-assisted manuscripts for 2026 journal desks: integrity checks, journal ranking by AI policy, venue adaptation, content-preserving copy editing. Claude Code and Codex plugin.

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    dna-seq/manuscript-skills's past year of commit activity
    Python 5 MIT 1 0 0 Updated Nov 9, 2026
  • just-dna-lite Public

    lite and fast version of just-dna-seq personalized genomic platform

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    dna-seq/just-dna-lite's past year of commit activity
    Python 143 AGPL-3.0 14 12 1 Updated Nov 5, 2026
  • dna-seq-claude-marketplace Public

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    dna-seq/dna-seq-claude-marketplace's past year of commit activity
    0 1 0 0 Updated Nov 5, 2026
  • prepare-annotations Public

    Pipelines to prepare annotations

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    dna-seq/prepare-annotations's past year of commit activity
    Python 1 MIT 1 0 0 Updated Nov 4, 2026
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@antonkulaga @winternewt @Alex-Karmazin

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