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GeezerVison is showing myriad.com — Gene Table | Myriad Genetics

Gene Table

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  • Associated Genes

  • Associated Syndromes

Print gene table Print syndromes table
  • Genes Breast Ovarian Colorectal Uterine Skin Pancreatic Gastric Prostate Renal Lung Endocrine Other
  • Genes Breast Ovarian Colorectal Uterine Skin Pancreatic Gastric Prostate Renal Lung Endocrine Other

In addition to the genes listed above, Myriad Genetics MyRisk® Hereditary Cancer Test includes RiskScore® Assessment, a precision medicine tool that predicts a woman’s five year and lifetime risk for developing breast cancer. RiskScore analyzes over 385 validated genetic and risk markers combined with the Tyrer-Cuzick model to estimate a woman’s risk for developing breast cancer.

RiskScore is calculated for women under age 85 without a personal history of breast cancer, LCIS, hyperplasia, atypical hyperplasia, or a breast biopsy with unknown results. RiskScore is not calculated if the patient is known to carry a mutation in a breast cancer risk gene other that CHEK2, or if there are any known mutations in high-penetrance breast cancer risk genes in the patient’s family.

To learn more about RiskScore assessment and the medical management guidelines provided for patients identified to have a remaining lifetime risk of breast cancer >20%, you may view the result insert by clicking the link below.

View RiskScore Insert

Genes selected for MyRisk satisfy these criteria:

  • Cancer Focus
    • Heritable contribution
    • Association with overlapping syndromes
  • Penetrance
    • Cancer risk is at least 2-3 times the general population
  • Clinically Significant
    • Based on increased cancer risk from societal guidelines or determined by multiple studies
    • Change in management inferred based on risk level

Each gene tested with the MyRisk Test links to one or more of 11 cancer sites:
Breast, Ovarian, Colorectal, Uterine, Skin, Pancreatic, Gastric, Prostate, Renal, Lung, and Endocrine.

The MyRisk Test simplifies the test selection process by providing you the most comprehensive hereditary cancer panel test with clinically significant results. Rest assured you’re testing for the most clinically significant genes tied to your patients’ risk.

Powerful tests to illuminate life-changing insights

  • Identifies risk of developing 11 hereditary cancers

    Learn more
  • Identifies actionable genomic variants and biomarkers associated with FDA-approved therapies

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  • Identifies HRD status to inform treatment strategies

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  • Identifies prostate cancer aggressiveness to inform treatment strategies

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  • Identifies risk of developing 11 hereditary cancers leveraging family history of certain cancers

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  • Identifies at-risk couples for a pregnancy affected by inherited conditions

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  • Identifies risk of chromosomal conditions for expectant parents

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  • Identifies fetal sex as early as six weeks into pregnancy

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  • Identifies how genes affect outcomes with certain mental health medications

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