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#

multiple-sequence-alignment

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Here are 143 public repositories matching this topic...

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All 143 Python 59 C++ 13 Jupyter Notebook 11 C 10 Java 7 HTML 5 JavaScript 5 R 5 Rust 5 Shell 5
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ColabFold

sokrypton / ColabFold

Star 3k

Making Protein folding accessible to all!

bioinformatics protein-structure structure-prediction multiple-sequence-alignment
  • Updated Nov 9, 2026
  • Jupyter Notebook

microsoft / evodiff

Star 691

Generation of protein sequences and evolutionary alignments via discrete diffusion models

generative-model protein-sequences multiple-sequence-alignment discrete-diffusion
  • Updated Jan 15, 2026
  • Python

refresh-bio / FAMSA

Star 279

Algorithm for ultra-scale multiple protein sequence alignments: 3 million ABC transporters analyzed in 5 minutes and 18 GB of RAM.

bioinformatics proteomics longest-common-subsequence pfam multiple-sequence-alignment sequence-similarity guide-tree
  • Updated Sep 10, 2026
  • C++

inab / trimal

Star 273

A tool for automated alignment trimming in large-scale phylogenetic analyses. Development version: 2.0

trimming multiple-sequence-alignment bioinformatics-tool
  • Updated Nov 11, 2026
  • C++
pyMSAviz

moshi4 / pyMSAviz

Star 205

MSA(Multiple Sequence Alignment) visualization python package for sequence analysis

visualization python bioinformatics genomics matplotlib sequence-alignment msa sequence-analysis multiple-sequence-alignment
  • Updated Dec 1, 2024
  • Python

yangao07 / abPOA

Star 149

abPOA: an SIMD-based C library for fast partial order alignment using adaptive band

simd long-reads multiple-sequence-alignment partial-order-alignment consensus-sequences banded-dp consensus-sequence alignment-graph gfa-format
  • Updated Nov 5, 2026
  • C

diegozea / MIToS.jl

Star 86

A Julia package to analyze protein sequences, structures, and evolutionary information

bioinformatics biology proteins pdb protein-structure julia-language conservation mutual-information structural-bioinformatics protein-evolution pfam sifts multiple-sequence-alignment coevolution protein-sequence-analysis
  • Updated Oct 7, 2026
  • Julia

Sam-Sims / salti

Star 77

A fast, feature rich multiple sequence alignment browser for the terminal.

rust bioinformatics hpc tui msa multiple-sequence-alignment
  • Updated Oct 29, 2026
  • Rust

gcorso / NeuroSEED

Star 76

Implementation of Neural Distance Embeddings for Biological Sequences (NeuroSEED) in PyTorch (NeurIPS 2021)

machine-learning bioinformatics pytorch biological-sequences hierarchical-clustering multiple-sequence-alignment neurips-2021
  • Updated Oct 14, 2023
  • Python

elttaes / Revisiting-PLMs

Star 63

Exploring Evolution-aware & free protein language models as protein function predictors

benchmark pytorch contact-prediction stability multiple-sequence-alignment protein-annotation function-prediction protein-classification alphafold protein-language-model alphafold2 fitness-prediction zero-shot-prediction msa-construction msa-transformer esm1b remote-homology-detection metal-ion-binding
  • Updated Sep 28, 2024
  • Python

psipred / DMPfold2

Star 59

Fast and accurate protein structure prediction

deep-learning end-to-end multiple-sequence-alignment protein-structure-prediction
  • Updated Jan 17, 2025
  • Python

morispi / CONSENT

Star 56

Scalable long read self-correction and assembly polishing with multiple sequence alignment

assembly ngs consensus correction long self msa reads contigs long-reads multiple-sequence-alignment polishing self-correction
  • Updated Feb 6, 2024
  • C++
motif

jvogan / motif

Sponsor
Star 51

An AI-native molecular biology workbench for Claude Science: Claude opens sequence files and prepares analyses on request; you annotate, align, and review them in an interactive workspace.

bioinformatics mcp synthetic-biology computational-biology genbank crispr pcr plasmid molecular-biology sequence-alignment ai-agents claude primer-design sequence-analysis multiple-sequence-alignment bioinformatics-tool sanger-sequencing model-context-protocol mcp-app claude-science
  • Updated Oct 22, 2026
  • TypeScript

jasperlinthorst / reveal

Star 49

Graph based multi genome aligner

genome graph assembly gfa alignment reveal multiple-sequence-alignment
  • Updated Sep 17, 2021
  • Python

althonos / pyfamsa

Star 46

Cython bindings and Python interface to FAMSA, an algorithm for ultra-scale multiple sequence alignments.

bioinformatics genomics python-library python-bindings sequence-alignment cython-library multiple-sequence-alignment
  • Updated Mar 24, 2026
  • Cython

cmzmasek / archaeopteryx-js

Star 43

Archaeopteryx.js is a software tool for the visualization and analysis of highly annotated phylogenetic trees.

visualization javascript evolution phylogenetic-trees beast phylogenetics virology mrbayes archaeopteryx paleontology phylodynamics multiple-sequence-alignment phyloxml archaeopteryx-js nextstrain auspice treetime nexus-format
  • Updated Nov 6, 2026
  • JavaScript

thekaplanlab / msabrowser

Star 38

🧬 MSABrowser: dynamic and fast visualization of sequence alignments, variations, and annotations

bioinformatics genetics sequence-alignment msa protein-domains multiple-sequence-alignment msa-viewer sequence-alignment-visualization msabrowser
  • Updated May 21, 2024
  • JavaScript

jaswindersingh2 / SPOT-RNA2

Star 37

Improved RNA Secondary Secondary Structure Prediction using Evolutionary Profile, Mutational Coupling and Two-dimensional Transfer Learning

deep-learning transfer-learning multiple-sequence-alignment rna-secondary-structure canonical-base-pairs pseudoknot-base-pairs lone-pairs direct-coupling-analysis evolutionary-information non-canonical-base-pairs homologous-sequence spot-rna2 base-triples
  • Updated Apr 3, 2021
  • Perl

yangao07 / TideHunter

Star 37

TideHunter: efficient and sensitive tandem repeat detection from noisy long reads using seed-and-chain

tandem-repeats long-reads multiple-sequence-alignment seed-and-chain partial-order-alignment
  • Updated Mar 4, 2026
  • C

sanderlab / alignmentviewer

Star 35

Multiple sequence alignment visualizer

javascript html js protein alignment sequence-alignment msa multiple-sequence-alignment
  • Updated Jan 26, 2023
  • JavaScript

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