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Bioinformatics

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Bioinformatics is an interdisciplinary field that intersects with biology, computer science, mathematics and statistics. It concerns itself with the development and use of methods and software tools for collecting and analyzing biological data.

Here are 19,328 public repositories matching this topic...

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All 19,328 Python 7,889 Jupyter Notebook 2,075 R 1,892 HTML 1,066 Shell 666 Rust 578 C++ 573 JavaScript 491 TypeScript 376 Java 323
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Developer-Y / cs-video-courses

Star 84.8k

List of Computer Science courses with video lectures.

computer-science security machine-learning bioinformatics web-development reinforcement-learning computer-vision deep-learning algorithms robotics computational-biology databases embedded-systems systems computational-physics quantum-computing computer-architecture database-systems
  • Updated Nov 10, 2026

K-Dense-AI / scientific-agent-skills

Star 56.9k

Turn any AI agent into an AI Scientist. The #1 Agent Skills library for science, used by 250,000+ scientists worldwide. 177 ready-to-use validated skills plus 100+ scientific databases covering biology, chemistry, medicine, and drug discovery. Compatible with Cursor, Claude Code, Codex, Pi, Antigravity, and the open Agent Skills standard.

bioinformatics genomics computational-biology scientific-visualization scientific-computing drug-discovery data-analysis proteomics metabolomics chemoinformatics materials-science clinical-research claude ai-scientist agent-skills claudecode claude-skills
  • Updated Nov 9, 2026
  • Python

plotly / dash

Sponsor
Star 24.5k

Data Apps & Dashboards for Python. No JavaScript Required.

react python productivity flask finance data-science bioinformatics ai jupyter web-app plotly data-visualization dash dashboards gui-framework charting technical-computing plotly-dash
  • Updated Nov 10, 2026
  • Python

biopython / biopython

Star 5.3k

Official git repository for Biopython (originally converted from CVS)

python bioinformatics genomics protein-structure dna protein biopython phylogenetics sequence-alignment
  • Updated Nov 11, 2026
  • Python

synthetic-sciences / openscience

Star 4.4k

The open-source AI workbench for scientific research

agent cli open-source science opensource bioinformatics research ai ml scientific-computing bun ml-engineering ai-agent research-tools llm ai-scientist co-scientist
  • Updated Nov 12, 2026
  • TypeScript

danielecook / Awesome-Bioinformatics

Sponsor
Star 4.4k

A curated list of awesome Bioinformatics libraries and software.

awesome bioinformatics awesome-list
  • Updated Sep 27, 2026

seandavi / awesome-single-cell

Star 3.9k

Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc.

python bioinformatics clustering gene-expression data-visualization dimensionality-reduction awesome-list data-integration atac-seq single-cell rna-seq-data scrna-seq-data cell-differentiation gene-expression-profiles analysis-pipeline spatial-transcriptomics cell-populations rna-seq-experiments cell-clusters
  • Updated Nov 7, 2026

google / deepvariant

Star 3.8k

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

science machine-learning bioinformatics deep-learning genomics genome tensorflow ngs sequencing dna deep-neural-network deepvariant
  • Updated Oct 26, 2026
  • Python
nextflow

nextflow-io / nextflow

Star 3.5k

A workflow language for data-driven computational pipelines

docker groovy hello aws cloud bioinformatics pipeline nextflow hpc reproducible-research workflow-engine slurm pipeline-framework sge singularity reproducible-science dataflow singularity-containers
  • Updated Nov 12, 2026
  • Groovy
ColabFold

sokrypton / ColabFold

Star 3k

Making Protein folding accessible to all!

bioinformatics protein-structure structure-prediction multiple-sequence-alignment
  • Updated Nov 9, 2026
  • Jupyter Notebook
scanpy

scverse / scanpy

Star 2.6k

Single-cell analysis in Python. Scales to >100M cells.

python data-science machine-learning bioinformatics transcriptomics visualize-data scanpy anndata scverse
  • Updated Nov 12, 2026
  • Python

OpenGene / fastp

Star 2.5k

An ultra-fast all-in-one FASTQ preprocessor (QC/adapters/trimming/filtering/splitting/merging...)

adapter quality bioinformatics quality-control filter ngs sequencing overlap splitting duplication umi trimming preprocessing filtering illumina fastq merging qc polyg
  • Updated Oct 7, 2026
  • C++

lh3 / minimap2

Star 2.3k

A versatile pairwise aligner for genomic and spliced nucleotide sequences

bioinformatics genomics sequence-alignment spliced-alignment
  • Updated May 19, 2026
  • C
MMseqs2

soedinglab / MMseqs2

Star 2.2k

MMseqs2: ultra fast and sensitive search and clustering suite

bioinformatics taxonomy metagenomics alignment sequence-clustering profile-search sequence-search linclust mmseqs blast
  • Updated Nov 11, 2026
  • C

ai4s-research / awesome-ai-for-science

Star 2.1k

A curated list of awesome AI tools, libraries, papers, datasets, and frameworks that accelerate scientific discovery — from physics and chemistry to biology, materials, and beyond.

awesome bioinformatics awesome-list scientific-ai ai4science ai-for-science ai4s
  • Updated Nov 12, 2026

aipoch / medical-research-skills

Star 2k

Hundreds of agent skills for medical research, including protocol design, data analysis, evidence insights, and academic writing.

science bioinformatics ai genomics biology computational-biology data-visualization medical cancer-genomics data-analysis single-cell differential-expression medical-research
  • Updated Sep 17, 2026
  • Python

broadinstitute / gatk

Star 2k

Official code repository for GATK versions 4 and up

science bioinformatics spark genomics genome ngs sequencing dna gatk
  • Updated Nov 12, 2026
  • Java
scispacy

allenai / scispacy

Star 2k

A full spaCy pipeline and models for scientific/biomedical documents.

nlp bioinformatics spacy biomedical custom-pipes scientific-documents
  • Updated Dec 4, 2025
  • Python

galaxyproject / galaxy

Star 1.9k

Data intensive science for everyone.

science workflow bioinformatics pipeline genomics workflow-engine ngs sequencing dna usegalaxy hacktoberfest
  • Updated Nov 12, 2026
  • Python

bioconda / bioconda-recipes

Star 1.9k

Conda recipes for the bioconda channel.

bioinformatics conda hacktoberfest package-management
  • Updated Nov 12, 2026
  • Shell
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